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4-[(pyridine-2-yl) amino carbonyl] phenyl boronic acid

Acalacbrutinib intermediate by 4-[(pyridine-2-yl) amino carbonyl] phenyl boronic acid

4-[(pyridine-2-yl) amino carbonyl] phenyl boronic acid

INR 750

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Description

This compound is an intermediate, or precursor, in the multi-step chemical synthesis of acalabrutinib. Acalabrutinib is a kinase inhibitor used to treat mantle cell lymphoma and chronic lymphocytic leukemia.  CAS No: -850568-25-1

Specifications

Melting Point:  124–128°C
Synonyms:- (4-(Pyridin-2-ylcarbamoyl)phenyl)boronic acid, 4-(Pyridin-2-yl-aminocarbonyl)benzeneboronic acid, [4- [(Pyridin-2-yl)carbamoyl]phenyl]boronic acid, 4-(2-pyridylcarbamoyl)benzeneboronic acid, N-2- Pyridinyl 4-boronobenzamide
Packing :- Powder form :- 25 Kg in HEDP bag with 2 liners (5 layer protected bag)
Solubility:   Slightly soluble in water (1.8 g/L at 25°C)
Density: 1.33 g/cm³
Molecular Weight: 242.042 g/mol
Molecular Formula:  C₁₂H₁₁BN₂O₃